Yes — and this is one of its primary indications (Protocol C). RF and HIFU create a collagen-stimulating thermal response in the dermis without significant barrier disruption. Applying HPT78 immediately post-treatment introduces a targeted peptide signal that compounds the remodelling cascade at its peak. The bio-cellulose substrate also soothes any residual heat sensation. This is the cleanest, most direct application of the HPT78 amplification principle.

Yes — including as the primary post-treatment mask in suitable candidates where collagen stimulation and firming outcomes are the clinical priority. Just as a clinician may choose a deeper needling depth to prioritise structural remodelling over minimising recovery time, HPT78 may be selected first where firming is the objective. Where barrier recovery, nourishment, and maximum comfort are the priority, XT73 is the appropriate selection. Both may also be used in combination — XT73 immediately post-procedure, HPT78 introduced from day 2–3 once barrier has stabilised. Candidacy assessment should always guide the decision.

XT73 is the first responder: barrier stabilisation, anti-inflammatory modulation, and support for the skin's endogenous repair cascade. It is appropriate for every patient and every treatment, with no contraindications. HPT78 is the amplifier: peptide-driven collagen stimulation, fibroblast activation, and remodelling response extension for suitable candidates. It requires candidacy assessment and is not appropriate for all patients or all post-treatment states. The selection between them is a clinical assessment decision based on the patient’s skin condition, treatment type, and primary clinical objective. Both may also be used in combination — XT73 first for barrier support and nourishment, HPT78 introduced once barrier has recovered — where clinically appropriate.

Clients typically notice an immediate tightening and lifting sensation during the 20–25 minute application, driven by DMAE and the Argireline complex. Post-removal, visible contour improvement and skin firmness is apparent — particularly along the jawline, cheeks and under-eye area. The collagen synthesis benefits (Matrixyl 3000, EGF) compound over days to weeks of regular use.

Yes — 2 to 3 applications per week at home significantly extends the clinical lifting results between treatments. Prescribing HPT78 as a take-home protocol strengthens outcomes, builds patient compliance, and generates retail revenue. A box of 5 is a natural starter prescription after an in-clinic RF, HIFU, or anti-aging treatment.

For suitable candidates, yes. HPT78 is formulated without fragrance, essential oils, or known sensitisers. For Fitzpatrick IV–VI skin types with a history of post-inflammatory hyperpigmentation, refer to the candidacy guide — XT73 Restorative may be the more appropriate primary protocol, with HPT78 introduced cautiously and only after barrier recovery is confirmed.