Cosmacure
Cosmacure HTP78: Clinical Firming Masks
Cosmacure HTP78: Clinical Firming Masks
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HTP78 Clinical Biostimulating Mask — The Amplifier
Biostimulating Remodelling Amplification for Suitable Candidates.
Extend What Your Treatment Started.
The Cosmacure HTP78 is a medical-grade bio-cellulose biostimulating mask engineered to amplify the remodelling response in suitable candidates. Formulated around a high-performance peptide and collagen-stimulating complex, it engages fibroblast signalling pathways to extend and intensify the outcomes already initiated by the treatment — delivering measurable firming, lifting, and collagen synthesis support where the skin is primed to respond.
This is not a firming moisturiser. This is active biostimulation — a precision tool for the specific clinical moment when the skin is ready to be pushed further.
When to Select HTP78
Primary Protocol
Biostimulating Firming & Amplification
Selected when collagen stimulation and firming amplification are the primary clinical objective — for suitable candidates across all treatment types. Applied immediately post-treatment — including directly after microneedling, while the open microchannels give the peptide and growth-factor complex maximum access to the dermal level, where remodelling actually happens. The clinical decision between HTP78 and XT73 is based on patient assessment and treatment objectives.
Combined Protocol
With XT73 Restorative
Two sequences, chosen by clinical objective. Rejuvenation-led: HTP78 immediately — stimulate at the moment of maximum access — followed by XT73 at 24 and 48 hours to support repair through the recovery window. Recovery-led: XT73 immediately for barrier support and nourishment, with HTP78 introduced once the barrier has stabilised (24–72h) to engage the early remodelling window.
Candidacy assessment is required. HTP78 is not appropriate for all patients or all post-treatment states. Read the full candidacy guide and clinical research →
Why HTP78 Belongs in Your Treatment Room
Outcomes
Extended Treatment Results
Applied post-RF or HIFU, HTP78 amplifies collagen-stimulating signals already initiated by the device — extending the outcome beyond what the treatment alone achieves.
Revenue
Premium Protocol Step
Position HTP78 as a precision finishing step after lifting and contouring treatments. Clients feel and see the immediate firming effect — and that is memorable.
Clinical Narrative
Evidence-Backed Rationale
A protocol built on clinical logic — not just a product recommendation. Candidacy criteria and mechanistic rationale give practitioners a conversation that builds trust.
Retention
Prescribable Home Protocol
Prescribe 2–3 applications per week between appointments to maintain and extend clinical lifting results. Strong retail revenue driver with high patient compliance.
Clinical Benefits
Candidacy & When to Use HTP78
HTP78 is a precision tool, not a universal application. The following guide assists with protocol selection. Clinical judgement always takes precedence.
Suitable Candidate
- ✓Barrier intact or mildly disrupted
- ✓Fitzpatrick I–III, or IV–V with no PIH history
- ✓Treatment type: RF, HIFU, microcurrent, non-ablative
- ✓Protocol B: min. 24h post-XT73, erythema modulated
- ✓No active dermatitis, rosacea flare, or sensitisation
- ✓Patient goal: extending & amplifying results
Use XT73 Only
- ✗Significant barrier disruption present
- ✗Fitzpatrick IV–VI with elevated PIH risk
- ✗Ablative or aggressive peel within 72h
- ✗Active dermatitis, rosacea, or eczema
- ✗Known peptide sensitivity or high reactivity
- ✗Patient priority: comfort & conservative recovery
Read the full clinical research and candidacy framework →
Primary Treatment Indications
For microneedling, HTP78 may be selected as the primary post-treatment mask in suitable candidates where collagen stimulation and firming outcomes are the clinical priority — in the same way a clinician may choose a deeper needling depth to prioritise structural remodelling. Where barrier recovery and optimal nourishment are the priority, XT73 is the appropriate selection. Both may also be used in combination — XT73 immediately post-procedure, HTP78 introduced from day 2–3 once barrier has stabilised.
The HTP78 Active Complex
Three peptides: Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 (Matrixyl 3000), Dipeptide Diaminobutyroyl Benzylamide Diacetate, and Oligopeptide-1. Supporting actives: sodium hyaluronate, panthenol, centella asiatica, allantoin, beta-glucan, adenosine. Fragrance-free, essential-oil free, no colourants.
The Bio-Cellulose Delivery Advantage
HTP78 uses the same medical-grade bio-cellulose substrate as the XT73 — produced through bacterial fermentation, not a standard sheet mask. When working with high-performance peptides and growth factors, delivery is everything:
Sustained-release kinetics
Peptide actives released slowly and consistently over the contact period — maximising receptor engagement rather than delivering a single rapid bolus
Second-skin conformity
Nanofibrillar structure conforms to every facial contour — no air gaps, continuous ingredient contact across jaw, cheek, and eye areas
Enhanced penetration
Drives actives more effectively into the epidermis than standard cotton or hydrogel carriers — particularly relevant in the post-treatment state
Cooling comfort post-device
Naturally soothing on post-RF and post-HIFU skin, delivering the active payload while calming any residual heat sensation
Application Protocol
Complete procedure. Confirm candidacy. For Protocol C (RF/HIFU/microcurrent), apply immediately. For Protocol B, confirm barrier has stabilised (24–72h post-XT73).
Apply HTP78 onto clean skin. Smooth from centre outward, moulding firmly to facial contours including jaw and neck.
Leave on for 20–25 minutes. Optimal contact time for peptide complex absorption and receptor engagement.
Remove and press remaining serum into skin using upward lifting motions — do not rinse.
Follow with SPF. Prescribe take-home HTP78 for 3–5 additional days or 2–3 applications per week ongoing.
Pro tip: For Protocol C post-RF or HIFU, apply HTP78 while skin is still slightly warm from the treatment. Elevated skin temperature enhances peptide penetration and compounds the collagen-stimulating response.
Part of the Cosmacure Dual-Mask System
HTP78 & XT73: Two Products. Two Clinical Objectives. One System.
HTP78 is selected when collagen stimulation, firming amplification, and remodelling outcomes are the clinical priority in suitable candidates. Select by clinical objective, not by procedure alone. For patients where barrier restoration and intensive nourishment are the primary need, the XT73 Clinical Restorative Mask is the appropriate selection.
The First Responder
XT73 Restorative
Barrier restoration • Intensive nourishment • Anti-inflammatory • All skin types
View XT73 →You are here
HTP78 Firming
Collagen stimulation • Lifting • For suitable candidates
Read the clinical research behind the dual-protocol system →
What's in the Box
Each box contains individually sealed HTP78 Bio-Cellulose Masks — single-use, treatment-strength doses of the full HTP78 firming complex.
- Box of 5 — ideal for trialling post-RF or HIFU protocols, or prescribing for a targeted treatment course
- Box of 20 — best value for active clinical use or ongoing take-home lifting protocols
Frequently Asked Questions
Can HTP78 be used directly after RF or HIFU treatment? +
Yes — and this is one of its primary indications (Protocol C). RF and HIFU create a collagen-stimulating thermal response in the dermis without significant barrier disruption. Applying HTP78 immediately post-treatment introduces a targeted peptide signal that compounds the remodelling cascade at its peak. The bio-cellulose substrate also soothes any residual heat sensation. This is the cleanest, most direct application of the HTP78 amplification principle.
Can HTP78 be used after microneedling? +
Yes — including as the primary post-treatment mask in suitable candidates where collagen stimulation and firming outcomes are the clinical priority. Just as a clinician may choose a deeper needling depth to prioritise structural remodelling over minimising recovery time, HTP78 may be selected first where firming is the objective. Where barrier recovery, nourishment, and maximum comfort are the priority, XT73 is the appropriate selection. Both may also be used in combination — XT73 immediately post-procedure, HTP78 introduced from day 2–3 once barrier has stabilised. Candidacy assessment should always guide the decision.
What's the difference between HTP78 and XT73? +
XT73 is the first responder: barrier stabilisation, anti-inflammatory modulation, and support for the skin's endogenous repair cascade. It is appropriate for every patient and every treatment, with no contraindications. HTP78 is the amplifier: peptide-driven collagen stimulation, fibroblast activation, and remodelling response extension for suitable candidates. It requires candidacy assessment and is not appropriate for all patients or all post-treatment states. The selection between them is a clinical assessment decision based on the patient’s skin condition, treatment type, and primary clinical objective. Both may also be used in combination — XT73 first for barrier support and nourishment, HTP78 introduced once barrier has recovered — where clinically appropriate.
How quickly will clients see a firming result? +
The collagen synthesis benefits (Matrixyl 3000, EGF) compound over days to weeks of regular use.
Can clients use HTP78 at home between appointments? +
Yes — 2 to 3 applications per week at home significantly extends the clinical lifting results between treatments. Prescribing HTP78 as a take-home protocol strengthens outcomes, builds patient compliance, and generates retail revenue. A box of 5 is a natural starter prescription after an in-clinic RF, HIFU, or anti-aging treatment.
Is HTP78 suitable for all skin tones and types? +
For suitable candidates, yes. HTP78 is formulated without fragrance, essential oils, or known sensitisers. For Fitzpatrick IV–VI skin types with a history of post-inflammatory hyperpigmentation, refer to the candidacy guide — XT73 Restorative may be the more appropriate primary protocol, with HTP78 introduced cautiously and only after barrier recovery is confirmed.
Cosmacure Clinical Philosophy
Post-treatment skin that is ready to be biostimulated is different from post-treatment skin that needs to recover. HTP78 exists for the former — delivering active biostimulation at the precise clinical moment the skin is primed to respond. Knowing the difference is what the Cosmacure protocol system is built on.
Read the clinical research behind HTP78 and the Cosmacure protocol system →Share
